Cationic cell-penetrating peptides interfere with TNF signalling by induction of TNF receptor internalization
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چکیده
منابع مشابه
Cationic cell-penetrating peptides interfere with TNF signalling by induction of TNF receptor internalization.
Cationic cell-penetrating peptides (CPPs) have been used widely as delivery vectors for the import of molecules that otherwise do not cross the plasma membrane of eukaryotic cells. In this work, we demonstrate that the three cationic CPPs, Antennapedia homeodomain-derived peptide (Antp), nona-arginine and Tat-derived peptide, inhibit tumour necrosis factor (TNF)-mediated signal transduction. Th...
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*Department of Anatomy, Physiology, and Genetics and Institute for Molecular Medicine, Uniformed Services University School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814; †Cancer and Cell Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; and §Protein Expression Laboratory, National Cancer Institute SAIC, Nationa...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2005
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.02460